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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
acm5_human F130G acm5_human F130H acm5_human F130K
acm5_human F130M acm5_human F130Q acm5_human F130R
acm5_human F130S acm5_human F130T acm5_human F130X
acm5_human Y213 acm5_human C214 acm5_human S465Y
acm5_human T466P aa1r_bovin H251L aa1r_bovin I270M
aa1r_bovin H278L aa1r_human G14T aa1r_human E16A
aa1r_human P25L aa1r_human C46A aa1r_human C46S
aa1r_human D55A aa1r_human C85A aa1r_human C85S
aa1r_human P86F aa1r_human V87A aa1r_human L88A
aa1r_human T91A aa1r_human Q92A aa1r_human S94A
aa1r_human S94T aa1r_human L96F aa1r_human C131A
aa1r_human C131S aa1r_human H251L aa1r_human C255A
aa1r_human C255S aa1r_human I268C aa1r_human L269C
aa1r_human T270C aa1r_human Y271C aa1r_human I272C
aa1r_human A273C aa1r_human I274C aa1r_human F275C
aa1r_human L276C aa1r_human T277A aa1r_human T277C
aa1r_human T277S aa1r_human H278C aa1r_human H278L
aa1r_human G279C aa1r_human N280C aa1r_human S281C
aa1r_human A282C aa1r_human M283C aa1r_human N284C
aa1r_human P285C aa1r_human I286C aa1r_human V287C
aa1r_human Y288C aa1r_human A289C aa1r_human F290C
aa1r_mouse G14T aa1r_mouse E16A aa1r_mouse P25L
aa1r_mouse I31C aa1r_mouse C46A aa1r_mouse S50A
aa1r_mouse D55A aa1r_mouse L65F aa1r_mouse M82F
aa1r_mouse C85A aa1r_mouse C85S aa1r_mouse P86F
aa1r_mouse V87A aa1r_mouse L88A aa1r_mouse T91A
aa1r_mouse Q92A aa1r_mouse S93A aa1r_mouse S94A
aa1r_mouse S94T aa1r_mouse A125K aa1r_mouse C131A
aa1r_mouse S135A aa1r_mouse T141A aa1r_mouse F144L
aa1r_mouse H251L aa1r_mouse C255A aa1r_mouse I270M
aa1r_mouse I274A aa1r_mouse T277A aa1r_mouse T277S


Reference:

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