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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
grm4_rat T790-T823  [Contact Restraint] grm4_rat T823-W717  [Contact Restraint] grm4_rat W717-W798  [Contact Restraint]
grm4_rat W798-Y627  [Contact Restraint] grm4_rat Y627-Y667  [Contact Restraint] grm4_rat Y667-Y759  [Contact Restraint]
grm4_rat Y759-Y792  [Contact Restraint] grm4_rat Y792-Y838  [Contact Restraint] grm4_rat Y838-V596  [Contact Restraint]
grm4_rat V596-V628  [Contact Restraint] grm4_rat V628-V716  [Contact Restraint] grm4_rat V716-V765  [Contact Restraint]
grm4_rat V765-V797  [Contact Restraint] grm4_rat V797-V824  [Contact Restraint] c5ar_human G210-M120  [Contact Restraint]
c5ar_human M120-G210  [Contact Restraint] aa1r_human L65-M82  [Contact Restraint] agtra_rat N111-H256  [Contact Restraint]
ednrb_rat D368-S342  [Contact Restraint] nk2r_human N51-D79  [Contact Restraint] oprm_rat Y148-W318  [Contact Restraint]
5ht1b_human S212-F331  [Contact Restraint] ada2c_rat V188-Y210  [Contact Restraint] gnrhr_human F307-P282  [Contact Restraint]
drd2_human D114-D80  [Contact Restraint] drd2_human M88-F110  [Contact Restraint] oprx_rat L98-A125  [Contact Restraint]
oprx_rat A125-Q277  [Contact Restraint] oprx_rat Q277-T302  [Contact Restraint] oprx_rat T302-A213  [Contact Restraint]
oprx_rat A213-L56  [Contact Restraint] fshr_rat D407-Y548  [Contact Restraint] ada1b_mesau Y348-C128  [Contact Restraint]
ada1b_mesau C128-F310  [Contact Restraint] opsd_bovin E122-M86  [Contact Restraint] adrb2_human D113-N312  [Contact Restraint]
ada1a_rat F163-F187  [Contact Restraint] adrb2_mesau A202-Q170  [Contact Restraint] drd4_rat F88-M109  [Contact Restraint]
drd4_rat M109-L87  [Contact Restraint] 5ht1b_human C326-D352  [Contact Restraint] 5ht2a_rat D155-N363  [Contact Restraint]
agtra_rat L112-Y292  [Contact Restraint] agtra_rat Y292-N111  [Contact Restraint] gnrr2_claga D90-D321  [Contact Restraint]
gabr1_rat A633-A711  [Contact Restraint] gabr1_rat A711-A818  [Contact Restraint] gabr1_rat A818-A838  [Contact Restraint]
gabr1_rat A838-D720  [Contact Restraint] gabr1_rat D720-C636  [Contact Restraint] gabr1_rat C636-C846  [Contact Restraint]
gabr1_rat C846-Q728  [Contact Restraint] gabr1_rat Q728-G635  [Contact Restraint] gabr1_rat G635-G670  [Contact Restraint]
gabr1_rat G670-G714  [Contact Restraint] gabr1_rat G714-G805  [Contact Restraint] gabr1_rat G805-G836  [Contact Restraint]
gabr1_rat G836-I684  [Contact Restraint] gabr1_rat I684-I726  [Contact Restraint] gabr1_rat I726-I815  [Contact Restraint]
gabr1_rat I815-I839  [Contact Restraint] gabr1_rat I839-L631  [Contact Restraint] gabr1_rat L631-L668  [Contact Restraint]
gabr1_rat L668-L715  [Contact Restraint] gabr1_rat L715-L809  [Contact Restraint] gabr1_rat L809-L845  [Contact Restraint]
gabr1_rat L845-K683  [Contact Restraint] gabr1_rat K683-K807  [Contact Restraint] gabr1_rat K807-M680  [Contact Restraint]
gabr1_rat M680-M719  [Contact Restraint] gabr1_rat M719-M837  [Contact Restraint] gabr1_rat M837-F644  [Contact Restraint]
gabr1_rat F644-F673  [Contact Restraint] gabr1_rat F673-F803  [Contact Restraint] gabr1_rat F803-P645  [Contact Restraint]
gabr1_rat P645-P851  [Contact Restraint] gabr1_rat P851-S637  [Contact Restraint] gabr1_rat S637-S674  [Contact Restraint]
gabr1_rat S674-T632  [Contact Restraint] gabr1_rat T632-T682  [Contact Restraint] gabr1_rat T682-T712  [Contact Restraint]
gabr1_rat T712-T849  [Contact Restraint] gabr1_rat T849-W667  [Contact Restraint] gabr1_rat W667-W727  [Contact Restraint]
gabr1_rat W727-Y677  [Contact Restraint] gabr1_rat Y677-Y710  [Contact Restraint] gabr1_rat Y710-Y804  [Contact Restraint]
gabr1_rat Y804-Y840  [Contact Restraint] gabr1_rat Y840-V634  [Contact Restraint] gabr1_rat V634-V687  [Contact Restraint]
gabr1_rat V687-V713  [Contact Restraint] gabr1_rat V713-V835  [Contact Restraint] gabr1_mouse A633-A711  [Contact Restraint]


Reference:

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