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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
oprm_rat S154-T207  [Contact Restraint] adrb2_human A46-A76  [Contact Restraint] adrb2_human D113-D79  [Contact Restraint]
adrb2_human D79-C116  [Contact Restraint] adrb2_human C116-C77  [Contact Restraint] adrb2_human G83-I112  [Contact Restraint]
adrb2_human F108-F166  [Contact Restraint] adrb2_human S111-S161  [Contact Restraint] adrb2_human S161-S203  [Contact Restraint]
adrb2_human T110-T164  [Contact Restraint] vipr1_rat V277-I298  [Contact Restraint] vipr1_rat I298-H355  [Contact Restraint]
vipr1_rat H355-Q382  [Contact Restraint] ada2a_mouse Y216-C117  [Contact Restraint] ssr2_human F296-P271  [Contact Restraint]
ssr2_human T301-W269  [Contact Restraint] acm3_rat A110-A150  [Contact Restraint] acm3_rat A150-A184  [Contact Restraint]
acm3_rat A184-A235  [Contact Restraint] acm3_rat A235-N122  [Contact Restraint] acm3_rat N122-N152  [Contact Restraint]
acm3_rat N152-D113  [Contact Restraint] acm3_rat D113-D147  [Contact Restraint] acm3_rat D147-C111  [Contact Restraint]
acm3_rat C111-G185  [Contact Restraint] acm3_rat G185-G233  [Contact Restraint] acm3_rat G233-I115  [Contact Restraint]
acm3_rat I115-I146  [Contact Restraint] acm3_rat I146-I188  [Contact Restraint] acm3_rat I188-I230  [Contact Restraint]
acm3_rat I230-L106  [Contact Restraint] acm3_rat L106-L142  [Contact Restraint] acm3_rat L142-L190  [Contact Restraint]
acm3_rat L190-L249  [Contact Restraint] acm3_rat L249-M121  [Contact Restraint] acm3_rat M121-M156  [Contact Restraint]
acm3_rat M156-M187  [Contact Restraint] acm3_rat M187-M241  [Contact Restraint] acm3_rat M241-F105  [Contact Restraint]
acm3_rat F105-F163  [Contact Restraint] acm3_rat F163-F196  [Contact Restraint] acm3_rat F196-F232  [Contact Restraint]
acm3_rat F232-P201  [Contact Restraint] acm3_rat P201-P242  [Contact Restraint] acm3_rat P242-S108  [Contact Restraint]
acm3_rat S108-S145  [Contact Restraint] acm3_rat S145-S195  [Contact Restraint] acm3_rat S195-T229  [Contact Restraint]
acm3_rat T229-W143  [Contact Restraint] acm3_rat W143-W192  [Contact Restraint] acm3_rat W192-W251  [Contact Restraint]
acm3_rat W251-Y104  [Contact Restraint] acm3_rat Y104-Y148  [Contact Restraint] acm3_rat Y148-Y240  [Contact Restraint]
acm3_rat Y240-V118  [Contact Restraint] acm3_rat V118-V149  [Contact Restraint] acm3_rat V149-V186  [Contact Restraint]
acm3_rat V186-V243  [Contact Restraint] acm3_rat V243-A71  [Contact Restraint] casr_human A772-A824  [Contact Restraint]
casr_human A824-A840  [Contact Restraint] casr_human A840-C731  [Contact Restraint] casr_human C731-C781  [Contact Restraint]
casr_human C781-C851  [Contact Restraint] casr_human C851-Q735  [Contact Restraint] casr_human Q735-G774  [Contact Restraint]
casr_human G774-G847  [Contact Restraint] casr_human G847-I736  [Contact Restraint] casr_human I736-I777  [Contact Restraint]
casr_human I777-I807  [Contact Restraint] casr_human I807-I839  [Contact Restraint] casr_human I839-L726  [Contact Restraint]
casr_human L726-L773  [Contact Restraint] casr_human L773-L812  [Contact Restraint] casr_human L812-L842  [Contact Restraint]
casr_human L842-M734  [Contact Restraint] casr_human M734-M771  [Contact Restraint] casr_human M771-M811  [Contact Restraint]
casr_human M811-F725  [Contact Restraint] casr_human F725-F775  [Contact Restraint] casr_human F775-F806  [Contact Restraint]
casr_human F806-F846  [Contact Restraint] casr_human F846-P823  [Contact Restraint] casr_human P823-S845  [Contact Restraint]
casr_human S845-T732  [Contact Restraint] casr_human T732-T780  [Contact Restraint] casr_human T780-T808  [Contact Restraint]
casr_human T808-W742  [Contact Restraint] casr_human W742-W818  [Contact Restraint] casr_human W818-Y744  [Contact Restraint]
casr_human Y744-Y779  [Contact Restraint] casr_human Y779-Y825  [Contact Restraint] casr_human Y825-Y858  [Contact Restraint]


Reference:

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