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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
lshr_rat T499-T584  [Contact Restraint] lshr_rat T584-W371  [Contact Restraint] lshr_rat W371-W495  [Contact Restraint]
lshr_rat W495-Y415  [Contact Restraint] lshr_rat Y415-Y459  [Contact Restraint] lshr_rat Y459-Y531  [Contact Restraint]
lshr_rat Y531-Y616  [Contact Restraint] lshr_rat Y616-V384  [Contact Restraint] lshr_rat V384-V451  [Contact Restraint]
lshr_rat V451-V507  [Contact Restraint] lshr_rat V507-V530  [Contact Restraint] lshr_rat V530-V613  [Contact Restraint]
lshr_rat V613-L369  [Contact Restraint] ssr1_mouse Y288-I192  [Contact Restraint] oprk_rat L185-M142  [Contact Restraint]
tshr_human A428-A457  [Contact Restraint] tshr_human A457-A497  [Contact Restraint] tshr_human A497-A538  [Contact Restraint]
tshr_human A538-A581  [Contact Restraint] tshr_human A581-A627  [Contact Restraint] tshr_human A627-A673  [Contact Restraint]
tshr_human A673-N432  [Contact Restraint] tshr_human N432-N455  [Contact Restraint] tshr_human N455-N590  [Contact Restraint]
tshr_human N590-N670  [Contact Restraint] tshr_human N670-D460  [Contact Restraint] tshr_human D460-D633  [Contact Restraint]
tshr_human D633-C454  [Contact Restraint] tshr_human C454-C539  [Contact Restraint] tshr_human C539-C598  [Contact Restraint]
tshr_human C598-C636  [Contact Restraint] tshr_human C636-C672  [Contact Restraint] tshr_human C672-E506  [Contact Restraint]
tshr_human E506-G431  [Contact Restraint] tshr_human G431-G464  [Contact Restraint] tshr_human G464-G498  [Contact Restraint]
tshr_human G498-G544  [Contact Restraint] tshr_human G544-I438  [Contact Restraint] tshr_human I438-I470  [Contact Restraint]
tshr_human I470-I515  [Contact Restraint] tshr_human I515-I541  [Contact Restraint] tshr_human I541-I583  [Contact Restraint]
tshr_human I583-I630  [Contact Restraint] tshr_human I630-I680  [Contact Restraint] tshr_human I680-L427  [Contact Restraint]
tshr_human L427-L456  [Contact Restraint] tshr_human L456-L507  [Contact Restraint] tshr_human L507-L551  [Contact Restraint]
tshr_human L551-L587  [Contact Restraint] tshr_human L587-L629  [Contact Restraint] tshr_human L629-L662  [Contact Restraint]
tshr_human L662-M463  [Contact Restraint] tshr_human M463-M542  [Contact Restraint] tshr_human M542-M637  [Contact Restraint]
tshr_human M637-F434  [Contact Restraint] tshr_human F434-F458  [Contact Restraint] tshr_human F458-F499  [Contact Restraint]
tshr_human F499-F550  [Contact Restraint] tshr_human F550-F585  [Contact Restraint] tshr_human F585-F631  [Contact Restraint]
tshr_human F631-F666  [Contact Restraint] tshr_human F666-P556  [Contact Restraint] tshr_human P556-P639  [Contact Restraint]
tshr_human P639-P668  [Contact Restraint] tshr_human P668-S472  [Contact Restraint] tshr_human S472-S505  [Contact Restraint]
tshr_human S505-S641  [Contact Restraint] tshr_human S641-S671  [Contact Restraint] tshr_human S671-T441  [Contact Restraint]
tshr_human T441-T496  [Contact Restraint] tshr_human T496-T588  [Contact Restraint] tshr_human T588-T632  [Contact Restraint]
tshr_human T632-W546  [Contact Restraint] tshr_human W546-Y466  [Contact Restraint] tshr_human Y466-Y510  [Contact Restraint]
tshr_human Y510-Y582  [Contact Restraint] tshr_human Y582-Y643  [Contact Restraint] tshr_human Y643-Y667  [Contact Restraint]
tshr_human Y667-V433  [Contact Restraint] tshr_human V433-V473  [Contact Restraint] tshr_human V473-V502  [Contact Restraint]
tshr_human V502-V543  [Contact Restraint] tshr_human V543-V584  [Contact Restraint] tshr_human V584-V628  [Contact Restraint]
tshr_human V628-V664  [Contact Restraint] tshr_human V664-I419  [Contact Restraint] oprd_rat T140-L219  [Contact Restraint]
oprm_rat I93-S145  [Contact Restraint] opsb_gecge H211-A132  [Contact Restraint] oprd_mouse S135-V188  [Contact Restraint]
oprm_rat S154-T207  [Contact Restraint] adrb2_human A46-A76  [Contact Restraint] adrb2_human D113-D79  [Contact Restraint]


Reference:

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