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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
fshr_human L460R fshr_human L460K fshr_human L460A
fshr_human L460D cnr2_human W172L cnr2_human W172Y
fshr_human F591S tshr_human P639S tshr_human A553T
lshr_human F576I lshr_human F576G lshr_human F576Y
lshr_human F576E lshr_human A373V lshr_human D578W
lshr_human L368P lshr_human L457R lshr_rat N539A
lshr_rat N539Q lshr_rat N539L lshr_rat N539D
lshr_rat N539H lshr_rat N619S lshr_rat N619E
lshr_rat E455A lshr_human D578H lshr_human I625K
lshr_human D405N lshr_human Y546F tshr_human Y601N
tshr_human Y601H tshr_human Y601F aa2br_human V11I
aa2br_human A12T aa2br_human L58V aa2br_human F59L
aa2br_human N273Y acm1_human V127-L131  [Contact Restraint] adrb1_melga C114-C199  [Contact Restraint]
adrb1_melga D121-N329  [Contact Restraint] adrb1_melga D121-S211  [Contact Restraint] adrb1_melga N329-S211  [Contact Restraint]
adrb1_melga S212-N310  [Contact Restraint] 5ht1a_human MSA  [Multi. Seq. Alignment] 5ht1b_human MSA  [Multi. Seq. Alignment]
5ht1d_human MSA  [Multi. Seq. Alignment] 5ht1e_human MSA  [Multi. Seq. Alignment] 5ht1f_human MSA  [Multi. Seq. Alignment]
5ht2a_human MSA  [Multi. Seq. Alignment] 5ht2b_human MSA  [Multi. Seq. Alignment] 5ht2c_human MSA  [Multi. Seq. Alignment]
5ht4r_human MSA  [Multi. Seq. Alignment] 5ht5a_human MSA  [Multi. Seq. Alignment] 5ht6r_human MSA  [Multi. Seq. Alignment]
5ht7r_human MSA  [Multi. Seq. Alignment] a0auj7_human MSA  [Multi. Seq. Alignment] a0n0n3_human MSA  [Multi. Seq. Alignment]
a0n0q0_human MSA  [Multi. Seq. Alignment] a0n0w6_human MSA  [Multi. Seq. Alignment] a0n0w7_human MSA  [Multi. Seq. Alignment]
a0n0w8_human MSA  [Multi. Seq. Alignment] a0n0w9_human MSA  [Multi. Seq. Alignment] a1a4v4_human MSA  [Multi. Seq. Alignment]
a1a4w1_human MSA  [Multi. Seq. Alignment] a1a5b2_human MSA  [Multi. Seq. Alignment] a1l485_human MSA  [Multi. Seq. Alignment]
a2bdz2_human MSA  [Multi. Seq. Alignment] a2bf34_human MSA  [Multi. Seq. Alignment] a2rrf6_human MSA  [Multi. Seq. Alignment]
a2rus0_human MSA  [Multi. Seq. Alignment] a3kme5_human MSA  [Multi. Seq. Alignment] a4d1u0_human MSA  [Multi. Seq. Alignment]
a4d1u1_human MSA  [Multi. Seq. Alignment] a4d2g5_human MSA  [Multi. Seq. Alignment] a4d2h9_human MSA  [Multi. Seq. Alignment]
a4fu14_human MSA  [Multi. Seq. Alignment] a4fva5_human MSA  [Multi. Seq. Alignment] a5juu3_human MSA  [Multi. Seq. Alignment]
a5juu5_human MSA  [Multi. Seq. Alignment] a7e1x5_human MSA  [Multi. Seq. Alignment] a8cah9_human MSA  [Multi. Seq. Alignment]
a8cai0_human MSA  [Multi. Seq. Alignment] a8cai1_human MSA  [Multi. Seq. Alignment] a8i0m1_human MSA  [Multi. Seq. Alignment]
a8k016_human MSA  [Multi. Seq. Alignment] a8k2h7_human MSA  [Multi. Seq. Alignment] a8k858_human MSA  [Multi. Seq. Alignment]
a8kag8_human MSA  [Multi. Seq. Alignment] a8mv66_human MSA  [Multi. Seq. Alignment] a8mzl3_human MSA  [Multi. Seq. Alignment]
aa1r_human MSA  [Multi. Seq. Alignment] aa2ar_human MSA  [Multi. Seq. Alignment] aa2br_human MSA  [Multi. Seq. Alignment]


Reference:

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