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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
gabr1_mouse V821 gabr1_mouse V841 gabr1_mouse V849
gabr1_mouse V850 gabr1_mouse V853 drd5_human L88F
agtra_rat P162Q agtra_rat G203A agtra_rat F77S
agtra_rat I38S agtra_rat F77V agtra_rat W253R
agtra_rat F77Y agtra_rat L212H agtra_rat L78F
agtra_rat F293L agtra_rat I201T agtra_rat F110C
agtra_rat L112A agtra_rat L143P agtra_rat L112S
agtra_rat F44H agtra_rat L112F agtra_rat L118H
agtra_rat I245T agtra_rat I245L agtra_rat F44T
agtra_rat V52R agtra_rat I38V agtra_rat L112H
agtra_rat F44S agtra_rat F44L ccr5_human A87
ccr5_human N48 ccr5_human N71 ccr5_human D76
ccr5_human G106 ccr5_human G44 ccr5_human G47
ccr5_human H88 ccr5_human I42 ccr5_human I52
ccr5_human I54 ccr5_human I56 ccr5_human I74
ccr5_human L36 ccr5_human L39 ccr5_human L50
ccr5_human L53 ccr5_human L55 ccr5_human L69
ccr5_human L70 ccr5_human L72 ccr5_human L77
ccr5_human L80 ccr5_human L81 ccr5_human M49
ccr5_human F41 ccr5_human F43 ccr5_human F45
ccr5_human F78 ccr5_human F79 ccr5_human F85
ccr5_human P84 ccr5_human S38 ccr5_human S75
ccr5_human T105 ccr5_human T82 ccr5_human W86
ccr5_human Y37 ccr5_human Y89 ccr5_human V40
ccr5_human V46 ccr5_human V51 ccr5_human V83
cxcr4_human A111 cxcr4_human A83 cxcr4_human A95
cxcr4_human N56 cxcr4_human D84 cxcr4_human G52
cxcr4_human G55 cxcr4_human G57 cxcr4_human H113
cxcr4_human I44 cxcr4_human I47 cxcr4_human I48
cxcr4_human I53 cxcr4_human I60 cxcr4_human I89
cxcr4_human L50 cxcr4_human L58 cxcr4_human L61


Reference:

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