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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
c5ar_human L118S c5ar_human L126I c5ar_human L118I
c5ar_human Y121D c5ar_human N119P c5ar_human L118V
c5ar_human L127I c5ar_human I116V c5ar_human T129S
c5ar_human N119I c5ar_human S123A c5ar_human A128V
c5ar_human L125Q c5ar_human N119Y c5ar_human L117V
c5ar_human I124R c5ar_human L117I c5ar_human N119K
c5ar_human L118H c5ar_human L117R c5ar_human A122C
c5ar_human I124F c5ar_human A128P c5ar_human L126A
c5ar_human T129A c5ar_human I130A c5ar_human R206H
c5ar_human L207A c5ar_human L207I c5ar_human Y222A
c5ar_human V260A c5ar_human F251A c5ar_human V286A
c5ar_human V286L c5ar_human S287A c5ar_human N296A
vipr1_human T343K vipr1_human T343C vipr1_human T343P
vipr1_human T343E vipr1_human T343A vipr1_human T343F
cnr2_human S112G aa1r_human G14 aa1r_human P25
aa1r_human I31 aa1r_human L65 aa1r_human M82
aa1r_human A125 aa1r_human F144 aa1r_human P86
aa1r_human L96 ccr5_cerae R163G ccr5_human G163R
agtra_rat N111K agtra_rat N111Q agtra_rat N111H
agtra_rat N111Y agtra_rat H256Y ednrb_rat S342A
nk2r_human N51D nk2r_human N51H nk2r_human N51S
nk2r_human D79E nk2r_human D79N nk2r_human N303A
nk2r_human N303D nk2r_human N303S acm1_rat L100A
acm1_rat L104A acm1_rat A103G acm1_rat V107A
acm1_rat A108G acm1_rat A111G acm1_rat M114A
acm1_rat L117A acm1_rat L118A acm1_rat F121A
oprm_rat Y148F oprm_rat W318A oprm_rat H319A
5ht1b_human S212A 5ht1b_human F331A pf2r_rat H81Q
pf2r_rat H81D pf2r_rat H81R pf2r_rat H81G
pf2r_rat H81A ada2c_rat V188 ada2c_rat Y210
ccr5_human V150 ccr5_cerae V150 c3ar_human Y160


Reference:

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