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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 2
Species	Mus musculus (Mouse)
Gene	P2ry2
Synonym	Purinergic receptor P2Y2 receptor P2Y2 P2Y purinoceptor 2 ATP receptor P2Y ATP receptor 2 P2U1 P2U purinoceptor 1 purinergic receptor P2Y [ Show all ]
Disease	N/A for non-human GPCRs
Length	373
Amino acid sequence	MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
UniProt	P35383
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075298
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL573824
Molecular formula	C6H11N2O12P3
IUPAC name	[2-(2,4-dioxopyrimidin-1-yl)ethoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular weight	396.077
Hydrogen bond acceptor	12
Hydrogen bond donor	5
XlogP	-4.8
Synonyms	N/A
Inchi Key	GLJLLLLDJHKXDS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H11N2O12P3/c9-5-1-2-8(6(10)7-5)3-4-18-22(14,15)20-23(16,17)19-21(11,12)13/h1-2H,3-4H2,(H,14,15)(H,16,17)(H,7,9,10)(H2,11,12,13)
PubChem CID	45481781
ChEMBL	CHEMBL573824
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
IC50	500000.0 nM	PMID19523835	ChEMBL
Inhibition	60.0 %	PMID19523835	ChEMBL

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