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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Bombesin receptor subtype-3
Species	Mus musculus (Mouse)
Gene	Brs3
Synonym	bb3 BB3 receptor bombesin like receptor 3 bombesin receptor subtype-3 BRS-3
Disease	N/A for non-human GPCRs
Length	399
Amino acid sequence	MSQRQSQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFALPEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYANHSDVPFVIIIFSRVLAFSNSCVNPFALYWLSKTFQQHFKAQLCCLKAEQPEPPLGDIPLNNLTVMGRVPATGSAHVSEISVTLFSGSSAKKGEDKV
UniProt	O54798
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075140
IUPHAR	40
DrugBank	N/A

Ligand

Name	CHEMBL1762259
Molecular formula	C19H24N4O3S
IUPAC name	1-tert-butyl-3-[4-(2,3-dihydro-1H-inden-1-ylamino)pyridin-3-yl]sulfonylurea
Molecular weight	388.486
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.9
Synonyms	BDBM50340976 (+/-)-N-(tert-butylcarbamoyl)-4-(2,3-dihydro-1H-inden-1-ylamino)pyridine-3-sulfonamide
Inchi Key	GHEZILJZCGFHBE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N4O3S/c1-19(2,3)22-18(24)23-27(25,26)17-12-20-11-10-16(17)21-15-9-8-13-6-4-5-7-14(13)15/h4-7,10-12,15H,8-9H2,1-3H3,(H,20,21)(H2,22,23,24)
PubChem CID	54583450
ChEMBL	CHEMBL1762259
IUPHAR	N/A
BindingDB	50340976
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	63.0 %	PMID21354793	ChEMBL
EC50	1300.0 nM	PMID21354793	BindingDB,ChEMBL

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