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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 1
Species	Mus musculus (Mouse)
Gene	Ffar1
Synonym	FFA1 receptor FFA1R G protein-coupled receptor 40 G-protein coupled receptor 40 GPR40
Disease	N/A for non-human GPCRs
Length	300
Amino acid sequence	MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK
UniProt	Q76JU9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5411
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2315528
Molecular formula	C19H15NO2
IUPAC name	3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]phenyl]propanoic acid
Molecular weight	289.334
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.4
Synonyms	SCHEMBL1551054 3-(4-((2-(cyanomethyl)phenyl)ethynyl)phenyl)propanoic acid BDBM50425662
Inchi Key	AMKACOPNIVQTHQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H15NO2/c20-14-13-18-4-2-1-3-17(18)11-9-15-5-7-16(8-6-15)10-12-19(21)22/h1-8H,10,12-13H2,(H,21,22)
PubChem CID	67072752
ChEMBL	CHEMBL2315528
IUPHAR	N/A
BindingDB	50425662
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	398.11 nM	PMID23294321	ChEMBL

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