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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 6
Species	Homo sapiens (Human)
Gene	P2RY6
Synonym	pyrimidinergic receptor P2Y P2Y6 receptor P2Y6 P2Y purinoceptor 6 P2Y ATP receptor 6 uridine nucleotide receptor [ Show all ]
Disease	N/A
Length	328
Amino acid sequence	MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
UniProt	Q15077
Protein Data Bank	N/A
GPCR-HGmod model	Q15077
3D structure model	This predicted structure model is from GPCR-EXP Q15077.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4714
IUPHAR	326
DrugBank	N/A

Ligand

Name	BDBM50303345
Molecular formula	C13H16N2O12P2-2
IUPAC name	[but-3-ynoxy(oxido)phosphoryl] [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Molecular weight	454.221
Hydrogen bond acceptor	12
Hydrogen bond donor	3
XlogP	-3.8
Synonyms	Diphosphoric Acid 1-beta-(3-Butynyl)Ester 2-(Uridine-5''-yl)-ester, bis-Triethylammonium Salt
Inchi Key	FLMAOAJLSGOWQM-HJQYOEGKSA-L
Inchi ID	InChI=1S/C13H18N2O12P2/c1-2-3-6-24-28(20,21)27-29(22,23)25-7-8-10(17)11(18)12(26-8)15-5-4-9(16)14-13(15)19/h1,4-5,8,10-12,17-18H,3,6-7H2,(H,20,21)(H,22,23)(H,14,16,19)/p-2/t8-,10-,11-,12-/m1/s1
PubChem CID	91933956
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50303345
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1520.0 nM	PMID19902968	BindingDB

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