You can:
Name | Leukotriene B4 receptor 1 |
---|---|
Species | Homo sapiens (Human) |
Gene | LTB4R |
Synonym | BLT1 receptor BLTR Chemoattractant receptor-like 1 G-protein coupled receptor 16 GPR16 [ Show all ] |
Disease | Inflammatory disease Inflammatory bowel disease Human immunodeficiency virus infection Pancreatic cancer Psoriasis [ Show all ] |
Length | 352 |
Amino acid sequence | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN |
UniProt | Q15722 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q15722 |
3D structure model | This predicted structure model is from GPCR-EXP Q15722. |
BioLiP | N/A |
Therapeutic Target Database | T59626 |
ChEMBL | CHEMBL3911 |
IUPHAR | 267 |
DrugBank | BE0003490 |
Name | CHEMBL109015 |
---|---|
Molecular formula | C20H25ClO2S |
IUPAC name | 7-[5-[3-(4-chlorophenyl)propyl]thiophen-3-yl]heptanoic acid |
Molecular weight | 364.928 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 1 |
XlogP | 6.6 |
Synonyms | 7-{5-[3-(4-Chloro-phenyl)-propyl]-thiophen-3-yl}-heptanoic acid BDBM50001158 7-[5-[3-(4-Chlorophenyl)propyl]-3-thienyl]heptanoic acid |
Inchi Key | FKMBIKUSMNUQPZ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H25ClO2S/c21-18-12-10-16(11-13-18)7-5-8-19-14-17(15-24-19)6-3-1-2-4-9-20(22)23/h10-15H,1-9H2,(H,22,23) |
PubChem CID | 15666578 |
ChEMBL | CHEMBL109015 |
IUPHAR | N/A |
BindingDB | 50001158 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 1000.0 nM | PMID1324316 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417