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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Rattus norvegicus (Rat)
Gene	Adora1
Synonym	A1 receptor A1-AR A1R adenosine receptor A1 RDC7
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
UniProt	P25099
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL318
IUPHAR	18
DrugBank	N/A

Ligand

Name	Adenosine-5'-(N-methoxy)carboxamide hydrate
Molecular formula	C11H14N6O5
IUPAC name	(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-methoxyoxolane-2-carboxamide
Molecular weight	310.27
Hydrogen bond acceptor	9
Hydrogen bond donor	4
XlogP	-1.0
Synonyms	54925-45-0 Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-methoxy-,hydrate BDBM50409302 5'-Oxo-5'-(methoxyamino)-5'-deoxyadenosine DTXSID40203437 AC1MIEGY (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-methoxyoxolane-2-carboxamide LS-143774 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-methoxyribofuranuronamide hydrate CHEMBL2113434 [ Show all ]
Inchi Key	FCAHXBLMILKKQK-QMWPFBOUSA-N
Inchi ID	InChI=1S/C11H14N6O5/c1-21-16-10(20)7-5(18)6(19)11(22-7)17-3-15-4-8(12)13-2-14-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,16,20)(H2,12,13,14)/t5-,6+,7-,11+/m0/s1
PubChem CID	3042985
ChEMBL	CHEMBL2113434
IUPHAR	N/A
BindingDB	50409302
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1620.0 nM	PMID10212124	ChEMBL
Ki	1960.0 nM	PMID10212124	ChEMBL

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