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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701929
Molecular formula	C17H18Cl2N2O
IUPAC name	N-[(3,4-dichlorophenyl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	337.244
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.7
Synonyms	US8802673, 30 BDBM129388 SCHEMBL12610157
Inchi Key	FBQKSMQDCGXVFK-QGZVFWFLSA-N
Inchi ID	InChI=1S/C17H18Cl2N2O/c18-15-6-1-12(9-16(15)19)10-21-14-4-2-13(3-5-14)17-11-20-7-8-22-17/h1-6,9,17,20-21H,7-8,10-11H2/t17-/m1/s1
PubChem CID	68325808
ChEMBL	CHEMBL3701929
IUPHAR	N/A
BindingDB	129388
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5.1 nM	, None	BindingDB,ChEMBL

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