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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B1 bradykinin receptor
Species	Macaca fascicularis (Crab-eating macaque)
Gene	BDKRB1
Synonym	B1R BK-1 receptor
Disease	N/A for non-human GPCRs
Length	352
Amino acid sequence	MASWPPLQLQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICSFGLLGNLFVLLVFLLPRRRLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGIIKANLFISIFLVVAISQDRYCVLVHPMASRRRQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILAFLLPLAAIIFFNYHILASLRGREEVSRTRCGGSKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFLAFTNSSLNPVIYVFAGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
UniProt	Q3BCU0
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5155
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL491240
Molecular formula	C26H24N8O2
IUPAC name	1-benzyl-N-[2-[methyl-[[4-(2H-tetrazol-5-yl)phenyl]methyl]amino]-2-oxoethyl]benzimidazole-2-carboxamide
Molecular weight	480.532
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.9
Synonyms	N-(2-((4-(1H-tetrazol-5-yl)benzyl)(methyl)amino)-2-oxoethyl)-1-benzyl-1H-benzo[d]imidazole-2-carboxamide BDBM50264679
Inchi Key	AKBYZCKEGIWISE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H24N8O2/c1-33(16-19-11-13-20(14-12-19)24-29-31-32-30-24)23(35)15-27-26(36)25-28-21-9-5-6-10-22(21)34(25)17-18-7-3-2-4-8-18/h2-14H,15-17H2,1H3,(H,27,36)(H,29,30,31,32)
PubChem CID	44580014
ChEMBL	CHEMBL491240
IUPHAR	N/A
BindingDB	50264679
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<5000.0 nM	PMID18752949	BindingDB,ChEMBL

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