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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Leukotriene B4 receptor 1
Species	Homo sapiens (Human)
Gene	LTB4R
Synonym	BLT1 receptor BLTR Chemoattractant receptor-like 1 G-protein coupled receptor 16 GPR16 P2Y7 P2Y purinoceptor 7 LTB4-R1 LTB4-R 1 [ Show all ]
Disease	Inflammatory disease Inflammatory bowel disease Human immunodeficiency virus infection Pancreatic cancer Psoriasis Cystic fibrosis Osteoporosis Renal cancer Rheumatoid arthritis Asthma Allergy [ Show all ]
Length	352
Amino acid sequence	MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
UniProt	Q15722
Protein Data Bank	N/A
GPCR-HGmod model	Q15722
3D structure model	This predicted structure model is from GPCR-EXP Q15722.
BioLiP	N/A
Therapeutic Target Database	T59626
ChEMBL	CHEMBL3911
IUPHAR	267
DrugBank	BE0003490

Ligand

Name	CHEMBL316674
Molecular formula	C28H30O5S
IUPAC name	3-[3-(2-carboxyethyl)-4-(6-phenylhexoxy)phenyl]sulfanylbenzoic acid
Molecular weight	478.603
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	7.0
Synonyms	5-(3-Hydroxycarbonylphenylthio)-2-(6-phenylhexyloxy)benzenepropanoic acid
Inchi Key	FBEMCSMSIPPNBK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H30O5S/c29-27(30)17-14-22-19-25(34-24-13-8-12-23(20-24)28(31)32)15-16-26(22)33-18-7-2-1-4-9-21-10-5-3-6-11-21/h3,5-6,8,10-13,15-16,19-20H,1-2,4,7,9,14,17-18H2,(H,29,30)(H,31,32)
PubChem CID	14739706
ChEMBL	CHEMBL316674
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	29.0 %	PMID2170647	ChEMBL
Inhibition	67.0 %	PMID2170647	ChEMBL
Inhibition	102.0 %	PMID2170647	ChEMBL

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