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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1830755
Molecular formula	C14H16F2N2O
IUPAC name	(4S)-4-[2-[1-(2,4-difluorophenyl)cyclopropyl]ethyl]-4,5-dihydro-1,3-oxazol-2-amine
Molecular weight	266.292
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.8
Synonyms	US8729113, 89 CHEMBL3652743 BDBM122355
Inchi Key	AJQUDOGDCBCJQP-JTQLQIEISA-N
Inchi ID	InChI=1S/C14H16F2N2O/c15-9-1-2-11(12(16)7-9)14(5-6-14)4-3-10-8-19-13(17)18-10/h1-2,7,10H,3-6,8H2,(H2,17,18)/t10-/m0/s1
PubChem CID	45101190
ChEMBL	CHEMBL3652743
IUPHAR	N/A
BindingDB	122355
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5.9 nM	, None	BindingDB,ChEMBL

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