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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 2
Species	Mus musculus (Mouse)
Gene	P2ry2
Synonym	Purinergic receptor P2Y2 receptor P2Y2 P2Y purinoceptor 2 ATP receptor P2Y ATP receptor 2 P2U1 P2U purinoceptor 1 purinergic receptor P2Y [ Show all ]
Disease	N/A for non-human GPCRs
Length	373
Amino acid sequence	MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
UniProt	P35383
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075298
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL574529
Molecular formula	C9H16N2O8P2
IUPAC name	5-(2,4-dioxopyrimidin-1-yl)pentyl-phosphonooxyphosphinic acid
Molecular weight	342.181
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	-2.6
Synonyms	BDBM50378132
Inchi Key	DWPOJFJAWGVQKN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H16N2O8P2/c12-8-4-6-11(9(13)10-8)5-2-1-3-7-20(14,15)19-21(16,17)18/h4,6H,1-3,5,7H2,(H,14,15)(H,10,12,13)(H2,16,17,18)
PubChem CID	45481636
ChEMBL	CHEMBL574529
IUPHAR	N/A
BindingDB	50378132
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	500000.0 nM	PMID19523835	BindingDB,ChEMBL
Inhibition	55.0 %	PMID19523835	ChEMBL

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