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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 4
Species	Homo sapiens (Human)
Gene	HTR4
Synonym	5-HT-4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5-HT4 receptor 5-HT4 serotonin receptor 4
Disease	N/A
Length	388
Amino acid sequence	MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
UniProt	Q13639
Protein Data Bank	N/A
GPCR-HGmod model	Q13639
3D structure model	This predicted structure model is from GPCR-EXP Q13639.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1875
IUPHAR	9
DrugBank	BE0000084

Ligand

Name	CHEMBL2179689
Molecular formula	C22H32N4O6
IUPAC name	N-[(1-butylpiperidin-4-yl)methyl]-5-methoxy-1-methylindazole-3-carboxamide;oxalic acid
Molecular weight	448.52
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	None
Synonyms	N/A
Inchi Key	AJARVXYYDRRYKK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H30N4O2.C2H2O4/c1-4-5-10-24-11-8-15(9-12-24)14-21-20(25)19-17-13-16(26-3)6-7-18(17)23(2)22-19;3-1(4)2(5)6/h6-7,13,15H,4-5,8-12,14H2,1-3H3,(H,21,25);(H,3,4)(H,5,6)
PubChem CID	71462663
ChEMBL	CHEMBL2179689
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	-9.0 %	PMID23043420	ChEMBL

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