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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Gonadotropin-releasing hormone receptor
Species	Macaca mulatta (Rhesus macaque)
Gene	GNRHR
Synonym	GnRH receptor GnRH-R
Disease	N/A for non-human GPCRs
Length	59
Amino acid sequence	VAFATSFTVCWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFAFLNPCFDPLIYGYFSL
UniProt	Q8SPZ1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5647
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Elagolix sodium
Molecular formula	C32H29F5N3NaO5
IUPAC name	sodium;4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoate
Molecular weight	653.582
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	None
Synonyms	AC-29671 DQYGXRQUFSRDCH-UQIIZPHYSA-M KB-76766 Sodium 4-(((1R)-2-(5-(2-fluoro-3-methoxyphenyl)-3-((2-fluoro-6-(trifluoromethyl)phenyl)methyl)-4-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)-1-phenylethyl)amino)butanoate Butanoic acid, 4-(((1R)-2-(5-(2-fluoro-3-methoxyphenyl)-3-((2-fluoro-6-(trifluoromethyl)phenyl)methyl)-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl)-1-phenylethyl)amino)-, monosodium salt Elagolix sodium salt NBI-56418 NA VA12044 5948VUI423 CS-0003317 EX-A2388 SCHEMBL1641994 AK554357 KS-0000063K sodium;4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoate Elagolix sodium [USAN] NBI-56418-NA 832720-36-2 D09336 HY-14369 sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate AKOS030524154 Elagolix sodium (USAN) MolPort-003-984-965 UNII-5948VUI423 4-((r)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2h-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid sodium salt CHEMBL502182 Elagolix sodium; NBI 56418NA SB16701 [ Show all ]
Inchi Key	DQYGXRQUFSRDCH-UQIIZPHYSA-M
Inchi ID	InChI=1S/C32H30F5N3O5.Na/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33;/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42);/q;+1/p-1/t25-;/m0./s1
PubChem CID	24785956
ChEMBL	CHEMBL502182
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3.3 nM	PMID19006286	ChEMBL

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