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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Delta-type opioid receptor
Species	Rattus norvegicus (Rat)
Gene	Oprd1
Synonym	opioid receptor OP1 DOR-1 DOR DOPr DOP delta receptor D-OR-1 Opioid receptor A [ Show all ]
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
UniProt	P33533
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL269
IUPHAR	317
DrugBank	N/A

Ligand

Name	CHEMBL2048970
Molecular formula	C20H27NO
IUPAC name	N-methyl-2-phenyl-N-[2-(3-phenylpropoxy)ethyl]ethanamine
Molecular weight	297.442
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.4
Synonyms	CHEMBL2079498 BDBM50386975
Inchi Key	DOQCHWAEKICHLH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H27NO/c1-21(15-14-20-11-6-3-7-12-20)16-18-22-17-8-13-19-9-4-2-5-10-19/h2-7,9-12H,8,13-18H2,1H3
PubChem CID	70688415
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50386975
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	8530.0 nM	PMID22677527	BindingDB

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