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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 2
Species	Mus musculus (Mouse)
Gene	Cnr2
Synonym	Peripheral cannabinoid receptor mCB2 CB2-R CB2 receptor CB2 CB-2 cannabinoid receptor 2 (spleen) cannabinoid receptor 2 (macrophage) rCB2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	347
Amino acid sequence	MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
UniProt	P47936
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5373
IUPHAR	57
DrugBank	N/A

Ligand

Name	CHEMBL74909
Molecular formula	C22H36FNO
IUPAC name	(5Z,8Z,11Z,14Z)-N-(2-fluoroethyl)icosa-5,8,11,14-tetraenamide
Molecular weight	349.534
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	6.4
Synonyms	SCHEMBL14455464 arachidonoyl-(2'-fluoroethyl)amide LMFA08020055 ZINC13782506 (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (2-fluoro-ethyl)-amide C22H36FNO N-(2-fluro-ethyl)-5Z,8Z,11Z,14Z-eicosatetraenoyl amine 166100-37-4 AC1NR2AA HMS3649B15 SR-01000946637 Arachidonoyl-2'-Fluoroethylamide MolPort-039-138-932 (5Z,8Z,11Z,14Z)-N-(2-fluoroethyl)icosa-5,8,11,14-tetraenamide N-(2-fluro-ethyl)arachidonoylamide 2'-Fluoro AEA Arachidonoyl 2'-fluoroethylamide Icosa-5,8,11,14-tetraenoic acid (2-fluoro-ethyl)-amide (0585) SR-01000946637-1 BDBM50072757 N-(2-fluro-ethyl) arachidonoyl amine 1350AH [ Show all ]
Inchi Key	DOGHEWWVBBVYEY-DOFZRALJSA-N
Inchi ID	InChI=1S/C22H36FNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
PubChem CID	5283436
ChEMBL	CHEMBL74909
IUPHAR	N/A
BindingDB	50072757
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	908.0 nM	PMID9876105	BindingDB,ChEMBL

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