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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A2b
Species	Rattus norvegicus (Rat)
Gene	Adora2b
Synonym	A2b A2B receptor A2BR adenosine receptor A2b
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
UniProt	P29276
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2592
IUPHAR	20
DrugBank	N/A

Ligand

Name	N'-hydroxy-2,3-dihydro-1,4-benzodioxine-3-carboximidamide
Molecular formula	C9H10N2O3
IUPAC name	N'-hydroxy-2,3-dihydro-1,4-benzodioxine-3-carboximidamide
Molecular weight	194.19
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.0
Synonyms	CHEMBL167380 1,4-Benzodioxin-2-carboximidamide, 2,3-dihydro-N-hydroxy- DTXSID10349412 AKOS017404970 CTK2I4504 85084-37-3 Maybridge3_004093 CTK8A6131 AC1LDC2K N'-Hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxamidine [ Show all ]
Inchi Key	AINNARSDQRBELY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H10N2O3/c10-9(11-12)8-5-13-6-3-1-2-4-7(6)14-8/h1-4,8,12H,5H2,(H2,10,11)
PubChem CID	645715
ChEMBL	CHEMBL167380
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Agonist potency	0.05 -	PMID6133953	ChEMBL

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