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GPCR

NameMu-type opioid receptor
SpeciesMus musculus (Mouse)
GeneOprm1
Synonymopioid receptor, mu 1
opioid receptor
OP3
Mu receptor
MOR-1
[ Show all ]
DiseaseN/A for non-human GPCRs
Length398
Amino acid sequenceMDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
UniProtP42866
Protein Data Bank4dkl, 5c1m, 6dde, 6ddf
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 4dkl.
BioLiPBL0416752, BL0416751, BL0321492, BL0224753, BL0224754, BL0224755,BL0224756, BL0321491
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2858
IUPHAR319
DrugBankN/A

Ligand

NameCHEMBL2442643
Molecular formulaC19H31NO
IUPAC name(2E,4E,8Z)-1-piperidin-1-yltetradeca-2,4,8-trien-1-one
Molecular weight289.463
Hydrogen bond acceptor1
Hydrogen bond donor0
XlogP5.3
Synonyms(2E,4E,8Z)-1-Piperidino-2,4,8-tetradecatriene-1-one
SCHEMBL20302088
Inchi KeyDHGGORSOUREXQR-INAOPUJYSA-N
Inchi IDInChI=1S/C19H31NO/c1-2-3-4-5-6-7-8-9-10-11-13-16-19(21)20-17-14-12-15-18-20/h6-7,10-11,13,16H,2-5,8-9,12,14-15,17-18H2,1H3/b7-6-,11-10+,16-13+
PubChem CID11173777
ChEMBLCHEMBL2442643
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
Ki7400.0 nMPMID24095014ChEMBL

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