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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Rattus norvegicus (Rat)
Gene	Adora1
Synonym	A1 receptor A1-AR A1R adenosine receptor A1 RDC7
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
UniProt	P25099
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL318
IUPHAR	18
DrugBank	N/A

Ligand

Name	1,7-dimethyl-8-phenyl-3H-purine-2,6-dione
Molecular formula	C13H12N4O2
IUPAC name	1,7-dimethyl-8-phenyl-3H-purine-2,6-dione
Molecular weight	256.265
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.0
Synonyms	AB-323/13887526 CHEMBL324138 1,7-dimethyl-8-phenyl-3,7-dihydro-1H-purine-2,6-dione Oprea1_862675 AC1LGJ72 MCULE-9124631956 ZINC339584 MolPort-002-799-251 [ Show all ]
Inchi Key	DFJWFVNLYOQXIS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H12N4O2/c1-16-9-10(15-13(19)17(2)12(9)18)14-11(16)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,15,19)
PubChem CID	822305
ChEMBL	CHEMBL324138
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kb	320.0 nM	PMID12139454	ChEMBL

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