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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-X-C chemokine receptor type 3
Species	Homo sapiens (Human)
Gene	CXCR3
Synonym	MigR IP-10 receptor Interferon-inducible protein 10 receptor GPR9 G protein-coupled receptor 9 Cxcr3 CXCR-3 CXC-R3 CKR-L2 chemokine (C-X-C motif) receptor 3 CD183 [ Show all ]
Disease	Inflammatory disease Autoimmune diabetes Inflammatory disorder Rheumatoid arthritis Psoriatic disorder
Length	368
Amino acid sequence	MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSETSEASYSGL
UniProt	P49682
Protein Data Bank	N/A
GPCR-HGmod model	P49682
3D structure model	This predicted structure model is from GPCR-EXP P49682.
BioLiP	N/A
Therapeutic Target Database	T25315
ChEMBL	CHEMBL4441
IUPHAR	70
DrugBank	N/A

Ligand

Name	CHEMBL1085258
Molecular formula	C29H28N2O4S
IUPAC name	N-benzyl-4-[[benzyl-(4-methoxyphenyl)sulfonylamino]methyl]benzamide
Molecular weight	500.613
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.8
Synonyms	SCHEMBL12863085 BDBM50320135 N-benzyl-4-((N-benzyl-4-methoxyphenylsulfonamido)methyl)benzamide
Inchi Key	AHMFXDVNFSUGOJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H28N2O4S/c1-35-27-16-18-28(19-17-27)36(33,34)31(21-24-10-6-3-7-11-24)22-25-12-14-26(15-13-25)29(32)30-20-23-8-4-2-5-9-23/h2-19H,20-22H2,1H3,(H,30,32)
PubChem CID	44253727
ChEMBL	CHEMBL1085258
IUPHAR	N/A
BindingDB	50320135
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	347.0 nM	PMID20483605	BindingDB,ChEMBL

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