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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL294394
Molecular formula	C15H19N3
IUPAC name	1-phenyl-4-(1H-pyrrol-2-ylmethyl)piperazine
Molecular weight	241.338
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.2
Synonyms	Piperazine, 1-phenyl-4-(1H-pyrrol-2-ylmethyl)- 245663-89-2 DTXSID70514604 1-Phenyl-4-[(1H-pyrrol-2-yl)methyl]piperazine ZINC13443853 1-Phenyl-4-(1H-pyrrol-2-ylmethyl)-piperazine KB-219694 2-(4-Phenylpiperazinomethyl)-1H-pyrrole BDBM50115719 CTK0J4786 1-phenyl-4-(1h-pyrrol-2-ylmethyl)piperazine [ Show all ]
Inchi Key	DCDSVYQQSBWIRG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H19N3/c1-2-6-15(7-3-1)18-11-9-17(10-12-18)13-14-5-4-8-16-14/h1-8,16H,9-13H2
PubChem CID	12997400
ChEMBL	CHEMBL294394
IUPHAR	N/A
BindingDB	50115719
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5400.0 nM	PMID12113813	BindingDB,ChEMBL

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