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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL14151033
Molecular formula	C19H21FN4O3
IUPAC name	6-ethyl-4-N-[3-fluoro-4-[(2S)-morpholin-2-yl]phenyl]pyridine-2,4-dicarboxamide
Molecular weight	372.4
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	0.9
Synonyms	US9029370, 117 BDBM158323
Inchi Key	BHJZDDKQAABURI-QGZVFWFLSA-N
Inchi ID	InChI=1S/C19H21FN4O3/c1-2-12-7-11(8-16(23-12)18(21)25)19(26)24-13-3-4-14(15(20)9-13)17-10-22-5-6-27-17/h3-4,7-9,17,22H,2,5-6,10H2,1H3,(H2,21,25)(H,24,26)/t17-/m1/s1
PubChem CID	71087007
ChEMBL	N/A
IUPHAR	N/A
BindingDB	158323
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	28.4 nM	N/A	BindingDB

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