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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Rattus norvegicus (Rat)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 Trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
UniProt	Q923Y9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3833
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1990021
Molecular formula	C16H15Cl2N3O2
IUPAC name	2,6-dichloro-N-[4-[(2S)-morpholin-2-yl]phenyl]pyridine-4-carboxamide
Molecular weight	352.215
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.6
Synonyms	4-Pyridinecarboxamide, 2,6-dichloro-N-[4-(2S)-2-morpholinylphenyl]- US9452980, 271 1312570-77-6 BDBM250361 ZINC117719453
Inchi Key	AIXPUCAPNGLHLG-CYBMUJFWSA-N
Inchi ID	InChI=1S/C16H15Cl2N3O2/c17-14-7-11(8-15(18)21-14)16(22)20-12-3-1-10(2-4-12)13-9-19-5-6-23-13/h1-4,7-8,13,19H,5-6,9H2,(H,20,22)/t13-/m1/s1
PubChem CID	87320650
ChEMBL	N/A
IUPHAR	N/A
BindingDB	250361
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	4.0 nM	N/A	BindingDB

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