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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuromedin-K receptor
Species	Rattus norvegicus (Rat)
Gene	Tacr3
Synonym	Tac3r SP-N receptor Nmkr NKR NK3 receptor NK-3R NK-3 receptor neuromedin K receptor neurokinin beta receptor Neurokinin B receptor Tachykinin receptor 3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	452
Amino acid sequence	MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRDPSANGCSHRGSKSASTTSSFISSPYTSVDEYS
UniProt	P16177
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3154
IUPHAR	362
DrugBank	N/A

Ligand

Name	CHEMBL2370069
Molecular formula	C50H71N13O11
IUPAC name	tert-butyl N-[(2S)-5-[[amino(nitramido)methylidene]amino]-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[(2R)-2-[(2S)-2-[[(2S)-1-amino-1-oxohexan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Molecular weight	1030.2
Hydrogen bond acceptor	12
Hydrogen bond donor	9
XlogP	3.5
Synonyms	N/A
Inchi Key	DBHBRBOJSGVFRU-QOWRJIHNSA-N
Inchi ID	InChI=1S/C50H71N13O11/c1-6-7-19-35(41(51)64)56-45(68)39-22-14-25-61(39)47(70)40-23-15-26-62(40)46(69)38(27-31-16-9-8-10-17-31)58-44(67)37(28-32-29-54-34-20-12-11-18-33(32)34)57-42(65)30(2)55-43(66)36(59-49(71)74-50(3,4)5)21-13-24-53-48(52)60-63(72)73/h8-12,16-18,20,29-30,35-40,54H,6-7,13-15,19,21-28H2,1-5H3,(H2,51,64)(H,55,66)(H,56,68)(H,57,65)(H,58,67)(H,59,71)(H3,52,53,60)/t30-,35-,36-,37+,38-,39-,40+/m0/s1
PubChem CID	14991669
ChEMBL	CHEMBL2370069
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
pKB	5.2 -	PMID1321907	ChEMBL

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