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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Formyl peptide receptor 2
Species	Mus musculus (Mouse)
Gene	Fpr2
Synonym	LXA4R Lipoxin A4 receptor-like protein FPRL1 N-formylpeptide receptor-like 2 FPRH2 FPRH1 FPR2A FPR2/ALX Fpr-rs2 Formylpeptide receptor-related sequence 2 formyl peptide receptor-like 1 formyl peptide receptor, related sequence 2 formyl peptide receptor 2 FMLPX ALXR ALX/FPR2 ALX RFP [ Show all ]
Disease	N/A for non-human GPCRs
Length	351
Amino acid sequence	MESNYSIHLNGSEVVVYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIVVDVNLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWIFALILTLPIFIFLTTVRIPGGDVYCTFNFGSWAQTDEEKLNTAITFVTTRGIIRFLIGFSMPMSIVAVCYGLIAVKINRRNLVNSSRPLRVLTAVVASFFICWFPFQLVALLGTVWFKETLLSGSYKILDMFVNPTSSLAYFNSCLNPMLYVFMGQDFRERFIHSLPYSLERALSEDSGQTSDSSTSSTSPPADIELKAP
UniProt	O88536
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	223
DrugBank	N/A

Ligand

Name	quin-C1
Molecular formula	C26H27N3O4
IUPAC name	4-butoxy-N-[2-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]benzamide
Molecular weight	445.519
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.1
Synonyms	786706-21-6 GTPL6265 4-butoxy-N-(2-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-3(4H)-yl)benzamide 4-butoxy-N-[2-(4-methoxyphenyl)-4-oxo-1,4-dihydro-2h-quinazolin-3-yl]benzamide AKOS027470217 MolPort-039-338-065 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide SCHEMBL19384377 D0C3HQ Quin C1 4-butoxy-N-[2-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]benzamide [ Show all ]
Inchi Key	XORVAHQXRDLSFT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27N3O4/c1-3-4-17-33-21-15-11-19(12-16-21)25(30)28-29-24(18-9-13-20(32-2)14-10-18)27-23-8-6-5-7-22(23)26(29)31/h5-16,24,27H,3-4,17H2,1-2H3,(H,28,30)
PubChem CID	11751175
ChEMBL	N/A
IUPHAR	6265
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	630.957 nM	PMID23160941	IUPHAR

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