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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 3
Species	Mus musculus (Mouse)
Gene	Lpar3
Synonym	Edg7 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 LPA receptor 3 LPA-3 LPA3 receptor Lysophosphatidic acid receptor Edg-7 [ Show all ]
Disease	N/A for non-human GPCRs
Length	354
Amino acid sequence	MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS
UniProt	Q9EQ31
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	274
DrugBank	N/A

Ligand

Name	D0SH0M
Molecular formula	C16H11NO5
IUPAC name	5-(4-methylphenoxy)-1,3-dioxoisoindole-2-carboxylic acid
Molecular weight	297.266
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	5-(4-methylphenoxy)-1,3-dioxoisoindole-2-carboxylic acid GTPL6989 compound 12 [PMID: 19800804]
Inchi Key	QSPCKQSNISDWOH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H11NO5/c1-9-2-4-10(5-3-9)22-11-6-7-12-13(8-11)15(19)17(14(12)18)16(20)21/h2-8H,1H3,(H,20,21)
PubChem CID	73755253
ChEMBL	N/A
IUPHAR	6989
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2992.0 nM	PMID19800804	IUPHAR

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