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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Adhesion G protein-coupled receptor G3
Species	Homo sapiens (Human)
Gene	ADGRG3
Synonym	ADGRG3 G-protein coupled receptor 97 G-protein coupled receptor PGR26 GPR97 (G protein-coupled receptor 97) Pb99
Disease	N/A
Length	549
Amino acid sequence	MATPRGLGALLLLLLLPTSGQEKPTEGPRNTCLGSNNMYDIFNLNDKALCFTKCRQSGSDSCNVENLQRYWLNYEAHLMKEGLTQKVNTPFLKALVQNLSTNTAEDFYFSLEPSQVPRQVMKDEDKPPDRVRLPKSLFRSLPGNRSVVRLAVTILDIGPGTLFKGPRLGLGDGSGVLNNRLVGLSVGQMHVTKLAEPLEIVFSHQRPPPNMTLTCVFWDVTKGTTGDWSSEGCSTEVRPEGTVCCCDHLTFFALLLRPTLDQSTVHILTRISQAGCGVSMIFLAFTIILYAFLRLSRERFKSEDAPKIHVALGGSLFLLNLAFLVNVGSGSKGSDAACWARGAVFHYFLLCAFTWMGLEAFHLYLLAVRVFNTYFGHYFLKLSLVGWGLPALMVIGTGSANSYGLYTIRDRENRTSLELCWFREGTTMYALYITVHGYFLITFLFGMVVLALVVWKIFTLSRATAVKERGKNRKKVLTLLGLSSLVGVTWGLAIFTPLGLSTVYIFALFNSLQGVFICCWFTILYLPSQSTTVSSSTARLDQAHSASQE
UniProt	Q86Y34
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	188
DrugBank	N/A

Ligand

Name	BECLOMETHASONE DIPROPIONATE
Molecular formula	C28H37ClO7
IUPAC name	[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
Molecular weight	521.047
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.0
Synonyms	AB1009261 LS-118439 Aldecina Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11.beta.,16.beta.)- Beclazone Prestwick_990 Beclometasone dipropionate Qvar 80 Beclomethasone dipropionate [USAN] SCH 18020W Beclovent (TN) UNII-5B307S63B2 C07813 Clenil-A 32278-EP2295408A1 DSSTox_RID_82926 5B307S63B2 HMS3259H03 Inalone O AC1Q62MZ MLS002154034 API0001601 Pregna-1-4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-,17,21-dipropionate Becloforte Propionic acid beclomethasone Beclometasone dipropionate for system suitability, European Pharmacopoeia (EP) Reference Standard Rhinosol Beclomethasone Dipropionate, Pharmaceutical Secondary Standard; Certified Reference Material SPBio_002790 Benconase Vanceril (TN) CCG-220855 CTK8F7938 32278-EP2311827A1 Entyderma 9-Chloro-11beta, 17,21-trihydroxy-16 beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate ZINC3938744 9-Chloro-11\|A,17,21-trihydroxy-16\|A-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate KUVIULQEHSCUHY-XYWKZLDCSA-N Alanase NCGC00094596-03 Beclacin Prestwick2_000855 Beclometasone (beclomethasone) dipropionate, British Pharmacopoeia (BP) Assay Standard Qvar Beclomethasone dipropionate (USP) Sanasthmax Becloturmant Tox21_113168 BRD-K97810537-001-13-6 Viarox CHEMBL1200500 2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate DSSTox_CID_28656 5534-09-8 HMS2097L11 [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate HMS3714L11 AC-2159 Menaderm Aldecine Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)- Beclazone 250 Propaderm Beclometasone dipropionate (JP17) Respocort Beclomethasone dipropionate, analytical standard, for drug analysis SCHEMBL6890 Beconase Vancenase C28H37ClO7 CPD001233361 32278-EP2301933A1 DTXSID3048730 9-AE-11\|A,17,21-EyoC>>u-16\|A-(1/4)x>>uOEthcThorn-1,4- paragraph signthornI(c)-3,20- paragraph signthornI feminine-17,21- paragraph signthorn+/-uEao yen Inalone R Aerobec MolPort-003-983-412 Atomase Prestwick0_000855 Beclomet QNASL Beclometasone dipropionato Rino-clenil Beclomethasone dipropionate, United States Pharmacopeia (USP) Reference Standard Spir BPBio1_000957 Vanceril Double Strength CHEBI:3002 (11beta,16beta)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione D00689 34135-07-4 GTPL5894 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate [(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate 9-chloro-16beta-methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate KW-053 Aldecin NCGC00179392-01 Beclate Prestwick3_000855 Beclometasone 17,21-dipropionate QVAR 40 Beclomethasone dipropionate [USAN:USP] Sanasthmyl Beclovent Turbinal BSPBio_000869 Clenil 32278-EP2281815A1 DSSTox_GSID_48730 HMS2235O23 HY-13571A AC1L2IWA MFCD00135613 AN-14214 Pregna-1,4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-, 17,21-dipropionate Beclocort Nasel Propaderm Forte Beclometasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard Rhino Clenil Beclomethasone dipropionate, anhydrous, European Pharmacopoeia (EP) Reference Standard SMR001233361 Beconase AQ Vanceril CAS-5534-09-8 CS-1503 32278-EP2305640A2 EINECS 226-886-0 9-Chloro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate W-5080 9-Chloro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate Korbutone AKOS015951275 NC00610 B4464 Prestwick1_000855 Beclomet Nasal Qnasl (TN) s3078 Beclorhinol ST24046007 BRD-K97810537-001-03-7 Ventolair (11beta,16beta)-9-chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate DB00394 534B098 HMS1570L11 [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate [ Show all ]
Inchi Key	KUVIULQEHSCUHY-XYWKZLDCSA-N
Inchi ID	InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
PubChem CID	21700
ChEMBL	CHEMBL1200500
IUPHAR	5894
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	3.1 nM	PMID22575658	IUPHAR

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