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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 5
Species	Mus musculus (Mouse)
Gene	Taar5
Synonym	mTaar5 PNR TAAR5 TaR-5 Trace amine receptor 5 Trimethylamine receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	337
Amino acid sequence	MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
UniProt	Q5QD14
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3784908
IUPHAR	170
DrugBank	N/A

Ligand

Name	N,N-DIMETHYLETHYLAMINE
Molecular formula	C4H11N
IUPAC name	N,N-dimethylethanamine
Molecular weight	73.139
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	0.7
Synonyms	AC1L1XZF C2H5N(CH3)2 Dimethylethylamine Ethyldimethylamine I14-19291 N,N-dimethyl-ethanamine N,N-Dimethylethylamine, purum, >=99.0% (GC) TR-020733 AKOS015903236 D0S5DR EINECS 209-940-8 FT-0082470 LS-168672 N,N-Dimethylethanamine NMe2Et ZINC2034511 70955-13-4 ANW-33376 dimethylaminoethane Ethanamine,N,N-dimethyl- HSDB 5712 MolPort-003-925-293 N,N-Dimethylethylamine, 99% SC-05626 ACMC-1AOTP CHEMBL609099 DTXSID4027232 EtNMe2 InChI=1/C4H11N/c1-4-5(2)3/h4H2,1-3H N,N-dimethyl-N-ethylamine N-Ethyldimethylamine TRA-0184555 Amines, C13-15-alkyldimethyl D1538 EINECS 275-053-8 FT-0600045 Methanamine, N-ethyl-N-methyl- N,N-dimethylethanaminium PubChem10322 9N5384XVEM C13-15-Alkyldimethylamines dimethylethyl amine Ethylamine, N,N-dimethyl- hydrogen 2-(dimethylamino)ethyl n,n-dimethyl ethyl amine N,N-Dimethylethylamine, >=99% TL80090781 AI3-52225 CTK3J0310 EC 209-940-8 F0001-1571 KS-00000UR1 n,n-dimethylaminoethane NEtMe2 UNII-9N5384XVEM 598-56-1 AN-21579 DAZXVJBJRMWXJP-UHFFFAOYSA-N Ethanamine, N,N-dimethyl- GTPL5523 MFCD00009039 RTR-020733 [ Show all ]
Inchi Key	DAZXVJBJRMWXJP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C4H11N/c1-4-5(2)3/h4H2,1-3H3
PubChem CID	11723
ChEMBL	N/A
IUPHAR	5523
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	700.0 nM	PMID17088868	IUPHAR

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