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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	B2 bradykinin receptor
Species	Mus musculus (Mouse)
Gene	Bdkrb2
Synonym	B2 receptor B2BKR B2BRA B2R BK-2 receptor BK2R bradykinin receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	392
Amino acid sequence	MPCSWKLLGFLSVHEPMPTAASFGIEMFNVTTQVLGSALNGTLSKDNCPDTEWWSWLNAIQAPFLWVLFLLAALENLFVLSVFFLHKNSCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWVFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMREYSEEGHNVTACVIVYPSRSWEVFTNVLLNLVGFLLPLSVITFCTVRILQVLRNNEMKKFKEVQTERKATVLVLAVLGLFVLCWVPFQISTFLDTLLRLGVLSGCWDEHAVDVITQISSYVAYSNSGLNPLVYVIVGKRFRKKSREVYRVLCQKGGCMGEPVQMENSMGTLRTSISVERQIHKLQDWAGKKQ
UniProt	P32299
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	42
DrugBank	N/A

Ligand

Name	des-Arg10-Kallidin
Molecular formula	C50H73N13O11
IUPAC name	(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Molecular weight	1032.21
Hydrogen bond acceptor	14
Hydrogen bond donor	11
XlogP	-3.8
Synonyms	GTPL644 Lys-[des-Arg9]BK AC1L3U7V Bradykinin, N2-L-lysyl-9-de-L-arginine- D05TZN kallidin1-9 SCHEMBL20298769 10-De-arg-kallidin BDBM50156454 Des-Arg10-Kallidin (Lys-des-Arg9 Bradykinin) Lys-des-arg(9)-BK [Lys-des-Arg9]-Bradykinin Bradykinin, lys-desarg(9) kallidin, des-Arg(10)- Lys-[Des-Arg9]Bradykinin (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine- AKOS024457490 Des-arg(10)-kallidin kallidin[1-9] [des-Arg10]kallidin BDBM50214792 DTXSID50222058 Lys-[des-Arg9]-bradykinin [Lys-des-Arg9]-Bradykinin, >=95% (HPLC) 71800-36-7 Bradykinin, lysyl-des-arginine(9) Kallidin, des-arginine(10)- NCGC00167261-01 (Des-Arg10)kallidin B5394 CHEMBL264100 Lys-(Des-Arg9)-Bradykinin [Lys,des-Arg9]bradykinin Bradykinin, lys-D-phe(8)-des-arg(9) [ Show all ]
Inchi Key	AILVBOHFGXNHCC-TZPCGENMSA-N
Inchi ID	InChI=1S/C50H73N13O11/c51-22-8-7-17-33(52)42(66)58-34(18-9-23-55-50(53)54)46(70)63-26-12-21-40(63)48(72)62-25-10-19-38(62)44(68)56-29-41(65)57-35(27-31-13-3-1-4-14-31)43(67)60-37(30-64)47(71)61-24-11-20-39(61)45(69)59-36(49(73)74)28-32-15-5-2-6-16-32/h1-6,13-16,33-40,64H,7-12,17-30,51-52H2,(H,56,68)(H,57,65)(H,58,66)(H,59,69)(H,60,67)(H,73,74)(H4,53,54,55)/t33-,34-,35-,36-,37-,38-,39-,40-/m0/s1
PubChem CID	122227
ChEMBL	CHEMBL264100
IUPHAR	644
BindingDB	50156454, 50214792
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	25118.9 nM	PMID8302267	IUPHAR

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