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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd1
Synonym	D1 receptor D1A DADR dopamine D1 receptor Dopamine-1A receptor Gpcr15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
UniProt	P18901
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL265
IUPHAR	214
DrugBank	N/A

Ligand

Name	CHEMBL299511
Molecular formula	C14H15NO2
IUPAC name	4-(2-aminoethyl)-3-phenylbenzene-1,2-diol
Molecular weight	229.279
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.2
Synonyms	BDBM50025204 D08YYX ZINC29559415 6-(2-Amino-ethyl)-biphenyl-2,3-diol
Inchi Key	DAKLNHHLHPIOPS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H15NO2/c15-9-8-11-6-7-12(16)14(17)13(11)10-4-2-1-3-5-10/h1-7,16-17H,8-9,15H2
PubChem CID	13678304
ChEMBL	CHEMBL299511
IUPHAR	N/A
BindingDB	50025204
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1500.0 nM	PMID3761310	BindingDB,ChEMBL

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