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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Substance-K receptor
Species	Cavia porcellus (Guinea pig)
Gene	TACR2
Synonym	Neurokinin A receptor NK-2 receptor NK-2R SKR Tachykinin receptor 2
Disease	N/A for non-human GPCRs
Length	402
Amino acid sequence	MGACVIVTNTNISSGLESNTTGITAFSMPTWQLALWATAYLALVLVAVTGNATVTWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAIDRYMAIVHPFQPRLSAPSTKAVIGGIWLVALALAFPQCFYSTITEDEGATKCVVAWPEDSRDKSLLLYHLVVIVLIYLLPLTVMFVAYSIIGLTLWRRAVPRHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNRRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSFSLRVNRCHTKEILFMAGDTVPSEATNGQAGGPQDRESVELSSLPGCRAGPSILAKASS
UniProt	Q64077
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2647
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL301437
Molecular formula	C26H34Cl2N2O2
IUPAC name	N-[2-(3,4-dichlorophenyl)-4-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]butyl]-N-methylbenzamide
Molecular weight	477.47
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.5
Synonyms	BDBM50071121 N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-hydroxy-1-methyl-ethyl)-piperidin-1-yl]-butyl}-N-methyl-benzamide
Inchi Key	DAJSDTWHSJMFGK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H34Cl2N2O2/c1-26(2,32)22-12-15-30(16-13-22)14-11-21(20-9-10-23(27)24(28)17-20)18-29(3)25(31)19-7-5-4-6-8-19/h4-10,17,21-22,32H,11-16,18H2,1-3H3
PubChem CID	44300632
ChEMBL	CHEMBL301437
IUPHAR	N/A
BindingDB	50071121
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
pKB	7.5 -	PMID9873462	ChEMBL

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