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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thyrotropin-releasing hormone receptor
Species	Rattus norvegicus (Rat)
Gene	Trhr
Synonym	Thyroliberin receptor TRH receptor TRH-R TRH-R1 TRH1 receptor
Disease	N/A for non-human GPCRs
Length	412
Amino acid sequence	MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTATNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTYVSTTKVSFDDTCLASEKNGPSSCTYGYSLTAKQEKI
UniProt	Q01717
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4553
IUPHAR	363
DrugBank	N/A

Ligand

Name	CHEMBL3897627
Molecular formula	C32H30N4O3
IUPAC name	2-[[(2S)-3-(1-benzylimidazol-4-yl)-1-(naphthalen-2-ylamino)-1-oxopropan-2-yl]amino]-3-phenylpropanoic acid
Molecular weight	518.617
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.0
Synonyms	N/A
Inchi Key	GNYRICYSVMQDDM-UFXYQILXSA-N
Inchi ID	InChI=1S/C32H30N4O3/c37-31(34-27-16-15-25-13-7-8-14-26(25)18-27)29(35-30(32(38)39)17-23-9-3-1-4-10-23)19-28-21-36(22-33-28)20-24-11-5-2-6-12-24/h1-16,18,21-22,29-30,35H,17,19-20H2,(H,34,37)(H,38,39)/t29-,30?/m0/s1
PubChem CID	134134558
ChEMBL	CHEMBL3897627
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	22.39 nM	None	ChEMBL

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