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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1833658
Molecular formula	C11H14N2O2
IUPAC name	(4S)-4-(2-phenoxyethyl)-4,5-dihydro-1,3-oxazol-2-amine
Molecular weight	206.245
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.3
Synonyms	AHFFIHVHUVGESC-VIFPVBQESA-N CHEMBL3652684 (S)-4-(2-Phenoxy-ethyl)-4,5-dihydro-oxazol-2-ylamine ZINC117256653 BDBM122294 US8729113, 1 [ Show all ]
Inchi Key	AHFFIHVHUVGESC-VIFPVBQESA-N
Inchi ID	InChI=1S/C11H14N2O2/c12-11-13-9(8-15-11)6-7-14-10-4-2-1-3-5-10/h1-5,9H,6-8H2,(H2,12,13)/t9-/m0/s1
PubChem CID	59173125
ChEMBL	CHEMBL3652684
IUPHAR	N/A
BindingDB	122294
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.7 nM	, None	BindingDB,ChEMBL

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