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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Rattus norvegicus (Rat)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 Trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
UniProt	Q923Y9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3833
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3942310
Molecular formula	C19H21FN4O3
IUPAC name	6-ethyl-4-N-[3-fluoro-4-[(2R)-morpholin-2-yl]phenyl]pyridine-2,4-dicarboxamide
Molecular weight	372.4
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	0.9
Synonyms	N/A
Inchi Key	BHJZDDKQAABURI-KRWDZBQOSA-N
Inchi ID	InChI=1S/C19H21FN4O3/c1-2-12-7-11(8-16(23-12)18(21)25)19(26)24-13-3-4-14(15(20)9-13)17-10-22-5-6-27-17/h3-4,7-9,17,22H,2,5-6,10H2,1H3,(H2,21,25)(H,24,26)/t17-/m0/s1
PubChem CID	134146108
ChEMBL	CHEMBL3942310
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	45.0 nM	None	ChEMBL

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