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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Galanin receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Galr1
Synonym	GAL1 receptor GAL1-R GALNR GALNR1 GALR-1
Disease	N/A for non-human GPCRs
Length	346
Amino acid sequence	MELAPVNLSEGNGSDPEPPAEPRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYYQRLFHRDSNQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCRVCNESPHGDAKEKNRIDTPPSTNCTHV
UniProt	Q62805
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5504
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3920910
Molecular formula	C11H11IO4S2
IUPAC name	2-(4-iodophenyl)-6,7-dihydro-5H-1,4-dithiepine 1,1,4,4-tetraoxide
Molecular weight	398.229
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	1.4
Synonyms	2-(4-Iodophenyl)-6,7-dihydro-5H-1,4-dithiepin 1,1,4,4-tetraoxide
Inchi Key	JSILNQRSSFZGDD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H11IO4S2/c12-10-4-2-9(3-5-10)11-8-17(13,14)6-1-7-18(11,15)16/h2-5,8H,1,6-7H2
PubChem CID	9843783
ChEMBL	CHEMBL3920910
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	22.3 %	None	ChEMBL
Inhibition	35.2 %	None	ChEMBL
Inhibition	37.0 %	None	ChEMBL
Inhibition	39.2 %	None	ChEMBL

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