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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Putative P2Y purinoceptor 10
Species	Mus musculus (Mouse)
Gene	P2ry10
Synonym	P2RY10 P2Y10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10
Disease	N/A for non-human GPCRs
Length	328
Amino acid sequence	MGSNSTSSAESNCNATYLPFQYSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHILSLPLRIYYYINRHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAVIWIVVGTACLPFPILRNAGLANSTDSCFADLGYKQMDAVVLVTMVVIAELAGFVIPVITIACCTWKTTVSLKHPPIAFQGISERKKALRMVFMCAAVFVICFTPYHINFIFYTMVKESIITSCPTVKSTLYFHPFSLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSRESGSSMVN
UniProt	Q8BFU7
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562168
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3813751
Molecular formula	C29H46NO10P
IUPAC name	(2S)-2-amino-3-[hydroxy-[[(2R,3R)-2-[3-(2-undecoxyphenyl)propanoyloxymethyl]-3,6-dihydro-2H-pyran-3-yl]oxy]phosphoryl]oxypropanoic acid
Molecular weight	599.658
Hydrogen bond acceptor	11
Hydrogen bond donor	3
XlogP	2.4
Synonyms	(2S)-2-Amino-3-[hydroxy[[(2R)-2alpha-[[3-[2-(undecyloxy)phenyl]propionyloxy]methyl]-3,6-dihydro-2H-pyran-3alpha-yl]oxy]phosphinyloxy]propionic acid BDBM50177142 SCHEMBL17309917
Inchi Key	ZEVJFWDTRLIRIP-WYMJOSIYSA-N
Inchi ID	InChI=1S/C29H46NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,13-16,24,26-27H,2-9,12,17-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26+,27+/m0/s1
PubChem CID	78319710
ChEMBL	CHEMBL3813751
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	41.69 nM	PMID27077565	ChEMBL
EC50	42.0 nM	PMID27077565	ChEMBL
Emax	12.4 %	PMID27077565	ChEMBL
Intrinsic activity	0.05 -	PMID27077565	ChEMBL

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