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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H1 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH1
Synonym	H1R HH1R
Disease	N/A for non-human GPCRs
Length	488
Amino acid sequence	MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFPITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGCIMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTFKRILRIPP
UniProt	P31389
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3943
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	1-Methylhistamine dihydrochloride
Molecular formula	C6H13Cl2N3
IUPAC name	2-(1-methylimidazol-4-yl)ethanamine;dihydrochloride
Molecular weight	198.091
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	None
Synonyms	2(1-Methyl-1H-imidazol-4-yl)-ethylamine bis hydrochloride C-0263 M 4910 SR-01000075290 Tox21_500757 1-Methyl-4-(beta-aminoethyl)imidazole dihydrochloride 2-(1-Methylimidazole-4-yl)ethanamine CHEMBL1487156 MolPort-004-946-867 AKOS016367671 KS-000019WB NS-01990 SR-01000075290-1 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrochloride CCG-222061 MCULE-1498707236 [2-(1-methyl-1H-imidazol-4-yl)ethyl]amine dihydrochloride 1-Methyl-4-(\|A-aminoethyl)imidazole dihydrochloride 6481-48-7 CS-0046885 NCGC00094097-01 1-Methylhistamine dihydrochloride, >=98% (TLC), powder AX8320530 LP00757 SCHEMBL1320841 ST085498 1-methyl-4-(2-aminoethyl)imidazole dihydrochloride 2-(1-Methyl-1H-imidazol-4-yl)ethanamine dihydrochloride MFCD00037000 1-METHYLHISTAMINE 2HCL AGXVEALMQHTMSW-UHFFFAOYSA-N EU-0100757 NCGC00261442-01 [ Show all ]
Inchi Key	AGXVEALMQHTMSW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H11N3.2ClH/c1-9-4-6(2-3-7)8-5-9;;/h4-5H,2-3,7H2,1H3;2*1H
PubChem CID	11957601
ChEMBL	CHEMBL1487156
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Activity	0.5 %	PMID7675	ChEMBL

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