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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Relaxin receptor 1
Species	Mus musculus (Mouse)
Gene	Rxfp1
Synonym	leucine-rich repeat-containing G-protein-coupled receptor 7 LGR7 Relaxin family peptide receptor 1 Leucine-rich repeat-containing G-protein coupled receptor 7 relaxin receptor 1 relaxin/insulin like family peptide receptor 1 RX1 RXFP1 RXFPR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	758
Amino acid sequence	MTSGPFFFCIFIIGKYFTLGSAQDVSCPLGSFPCGNMSRCLPQLLHCNGVDDCGNRADEDHCGDNNGWSLQLDKYFANYYKLASTNSFEAETSECLVGSVPMHCLCRDLELDCDEANLRAVPSVSSNVTVMSLQRNFIRTLPPNGFRKYHELQKLCLQNNRIHSVSVSAFRGLRSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLVLMNNALTRLPDKPLCQHMPRLHWLDFEGNRIHNLRNLTFISCNNLTVLVMRKNKINYLNEHAFTHLQKLDELDLGSNKIENLPPNIFKDLKELSQLNISYNPIQKIEVNQFDCLAKLKSLSLEGIEISNIQQRMFRPLINLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAITCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGVYLFVIGAFDLKFRGEYNKHAQPWMESVHCQFMGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPRKCRTITVLIFIWIIGFIVAFAPLGNKEFFKNYYGTNGVCFPLHSEDTGSTGAQIYSVVIFLGINLVAFIIIVFSYGSMFYSVHQSSVTVTEIQKQVKKEVVLAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPDSITSWVVIFILPINSALNPIIYTLTTRPFKEMIHQLWHNYRQRRSVDRKETQKAYAPSFIWVEMWPLQEMSSGFMKPGAFTDPCDLSLVSQSSRLNSYS
UniProt	Q6R6I7
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3714701
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	ML290
Molecular formula	C24H21F3N2O5S
IUPAC name	2-[(2-propan-2-yloxybenzoyl)amino]-N-[3-(trifluoromethylsulfonyl)phenyl]benzamide
Molecular weight	506.496
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.4
Synonyms	1482500-76-4 MLS004082009 ZINC199854172 D01WWO NCGC00250135-02 AS-16584 ML-290 SMR002850080 2-Isopropoxy-N-(2-((3-((trifluoromethyl)sulfonyl)phenyl)carbamoyl)phenyl)benzamide CHEMBL3716980 MolPort-039-138-787 AKOS032953991 GTPL8322 RXFP1-Agonist C24H21F3N2O5S SYN5228 2-[(2-propan-2-yloxybenzoyl)amino]-N-[3-(trifluoromethylsulfonyl)phenyl]benzamide compound 8 [PMID: 23764525] NCGC00250135-01 AOB4072 ML 290 SCHEMBL15528658 [ Show all ]
Inchi Key	RSYHJSDOGMSLDH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H21F3N2O5S/c1-15(2)34-21-13-6-4-11-19(21)23(31)29-20-12-5-3-10-18(20)22(30)28-16-8-7-9-17(14-16)35(32,33)24(25,26)27/h3-15H,1-2H3,(H,28,30)(H,29,31)
PubChem CID	56593349
ChEMBL	CHEMBL3716980
IUPHAR	8322
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	0.0 %	None	ChEMBL
Activity	44.4 %	None	ChEMBL

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