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GPCR

NameProbable G-protein coupled receptor 34
SpeciesHomo sapiens (Human)
GeneGPR34
SynonymGPR34
DiseaseN/A
Length381
Amino acid sequenceMRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST
UniProtQ9UPC5
Protein Data BankN/A
GPCR-HGmod modelQ9UPC5
3D structure modelThis predicted structure model is from GPCR-EXP Q9UPC5.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3562165
IUPHAR101
DrugBankN/A

Ligand

NameSCHEMBL3498604
Molecular formulaC31H26ClN3O4
IUPAC name2-[[6-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridine-2-carbonyl]amino]-3-(4-phenylmethoxyphenyl)propanoic acid
Molecular weight540.016
Hydrogen bond acceptor5
Hydrogen bond donor2
XlogP7.0
SynonymsCHEMBL3715199
Inchi KeyPTCKWBHTDIXPNJ-UHFFFAOYSA-N
Inchi IDInChI=1S/C31H26ClN3O4/c1-20-15-24(23-9-11-25(32)12-10-23)17-35-18-28(33-29(20)35)30(36)34-27(31(37)38)16-21-7-13-26(14-8-21)39-19-22-5-3-2-4-6-22/h2-15,17-18,27H,16,19H2,1H3,(H,34,36)(H,37,38)
PubChem CID59335735
ChEMBLCHEMBL3715199
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
IC501000.0 nMNoneChEMBL

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