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GPCR

Name	Olfactory receptor 5K1
Species	Homo sapiens (Human)
Gene	OR5K1
Synonym	HTPCRX10 Olfactory receptor OR3-8
Disease	N/A
Length	308
Amino acid sequence	MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProt	Q8NHB7
Protein Data Bank	N/A
GPCR-HGmod model	Q8NHB7
3D structure model	This predicted structure model is from GPCR-EXP Q8NHB7.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3721312
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Gamma-undecalactone
Molecular formula	C11H20O2
IUPAC name	5-heptyloxolan-2-one
Molecular weight	184.279
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.3
Synonyms	gamma-Undecanolactone KB-246110 NCGC00164025-01 .gamma.-n-Heptylbutyrolactone NSC46118 104-67-6 ST24044763 5-Heptyl-dihydrofuran-2(3H)-one Undecanoic acid, .gamma.-lactone AI3-00751 CAS-104-67-6 DSSTox_RID_79139 gamma-n-Heptylbutyrolactone gamma-Undecalactone (natural) gamma-Undekalakton [Czech] LS-2358 NSC 406421 .gamma.-Undecanolactone Peach lactone 4-Hydroxyundecanoic acid lactone TR-001023 5-Heptyldihydrofuran-2(3H)-one Undecanoic gamma-lactone Aldehyde C-14 peach EINECS 203-225-4 gamma-Undecalactone, analytical standard J-001223 MFCD00005405 .gamma.-Heptyl-.gamma.-butyrolactone NSC-76413 1,4-Hendecanolide PHXATPHONSXBIL-UHFFFAOYSA-N 5-heptyl-3,4,5-trihydrofuran-2-one Undecanoic .gamma.-lactone 57084-17-0 WLN: T5OVTJ E7 BDBM50168011 DSSTox_CID_14287 FT-0695781 gamma-Undecanolide KB-52236 NCGC00164025-02 .gamma.-Undecalactone NSC76413 176201-25-5 ST50826887 5-Heptyldihydro-2(3H)-furanone Undecanoic acid, 4-hydroxy-, .gamma.-lactone AK114195 CCRIS 1425 DTXSID4034287 gamma-Undecalactone, 98% HMS1786B22 M524 NSC-406421 .gamma.-Undecanolide Persicol 4-Hydroxyundecanoic acid, .gamma.-lactone U0003 5-heptyloxolan-2-one Undecanoic gamma-lactone, 99% AN-24690 CHEMBL195827 FEMA No. 3091 gamma-Undecalactone, natural (US), >=98%, FG Jsp000459 MolPort-001-783-108 .gamma.-Heptylbutyrolactone NSC406421 1,4-Undecanolide SCHEMBL113498 5-Heptyl-dihydro-furan-2-one Undecanoic ?-lactone AC1L1PDU xi-gamma-Undecalactone BRN 0081943 DSSTox_GSID_34287 gamma-Heptyl-gamma-butyrolactone gamma-UNDECALACTONE (ALDEHYDE C-14) FCC gamma-Undekalakton LMFA07040030 NCGC00254148-01 .gamma.-Undecalatone Peach aldehyde 2(3H)-Furanone, 5-heptyldihydro- Tox21_300063 5-Heptyldihydro-2(3H)-furanone # Undecanoic acid, 4-hydroxy-, gamma-lactone AKOS001076126 CHEBI:89362 EC 203-225-4 gamma-Undecalactone, >=98%, FCC, FG InChI=1/C11H20O2/c1-2-3-4-5-6-7-10-8-9-11(12)13-10/h10H,2-9H2,1H3 MCULE-9018416843 NSC-46118 .gamma.-Undekalakton PHXATPHONSXBIL-UHFFFAOYSA- 4-Undecanolide Undecan-4-olide 5-heptyltetrahydrofuran-2-one Undecanolide-1,4 AX8017400 Dihydro-5-heptyl-2(3H)-furanone FT-0626626 [ Show all ]
Inchi Key	PHXATPHONSXBIL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H20O2/c1-2-3-4-5-6-7-10-8-9-11(12)13-10/h10H,2-9H2,1H3
PubChem CID	7714
ChEMBL	CHEMBL195827
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	50.0 %	None	ChEMBL

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