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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Probable G-protein coupled receptor 34
Species	Mus musculus (Mouse)
Gene	Gpr34
Synonym	GPR34
Disease	N/A for non-human GPCRs
Length	375
Amino acid sequence	MTTTSVDSWLCSSHGMHFITNYSDQASQNFSGVPNVTSCPMDEKLLSTVLTTFYSVIFLVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRRAITTKQSIYVCCIVWTVALAGFLTMIILTLKKGGHNSTMCFHYRDRHNAKGEAIFNFVLVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIIHKTNEIMLVFSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQSEASRSESTSEFKPGHSLHDLSVTVKMPQYSTKGN
UniProt	Q9R1K6
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075291
IUPHAR	101
DrugBank	N/A

Ligand

Name	CHEMBL3815069
Molecular formula	C32H38NO11P
IUPAC name	(2S)-2-amino-3-[hydroxy-[(2R,3R)-2-[3-[2-[[3-(4-methylphenoxy)phenyl]methoxy]phenyl]propanoyloxymethyl]oxan-3-yl]oxyphosphoryl]oxypropanoic acid
Molecular weight	643.626
Hydrogen bond acceptor	12
Hydrogen bond donor	3
XlogP	1.0
Synonyms	BDBM50177130
Inchi Key	LBSSBBQXJGJPJY-GNSPLJBXSA-N
Inchi ID	InChI=1S/C32H38NO11P/c1-22-11-14-25(15-12-22)43-26-8-4-6-23(18-26)19-40-28-9-3-2-7-24(28)13-16-31(34)41-21-30-29(10-5-17-39-30)44-45(37,38)42-20-27(33)32(35)36/h2-4,6-9,11-12,14-15,18,27,29-30H,5,10,13,16-17,19-21,33H2,1H3,(H,35,36)(H,37,38)/t27-,29+,30+/m0/s1
PubChem CID	127051443
ChEMBL	CHEMBL3815069
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	35.48 nM	PMID27077565	ChEMBL
EC50	36.0 nM	PMID27077565	ChEMBL
Emax	15.2 %	PMID27077565	ChEMBL
Intrinsic activity	3.6 -	PMID27077565	ChEMBL

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