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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mas-related G-protein coupled receptor member X2
Species	Macaca mulatta (Rhesus macaque)
Gene	MRGPRX2
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	329
Amino acid sequence	MDPTTPAWGTESTTMNGNDQALPLLCGKETMISVFLILFIALVGLVGNAFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFQMTSCLAYLINFFGSISINIPSFFTVMTCAYLAGLSMLSAISTERCLSVLWPIWYRCRRPRHLSAVMCVLLWALSLLLSILEGKFCGFLFSDDDPGWCQTFDFITAAWLMFLFVVLCGSSLALLVRILCGSRSLPLTRLYLTILLTVLIFLLCGLPFGIQWFLILWIWKNSVVLFCHIHPISVVLSSFNSSANPIIYFFVGSFRKQWRLRQPILKLALQRALQDTAEVDHSEGCFSQGTLEMSRSSLV
UniProt	Q4QXU5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3831324
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3717645
Molecular formula	C36H37FN8O3
IUPAC name	(2S)-5-(diaminomethylideneamino)-2-[5-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-(3-phenoxyphenyl)benzimidazol-1-yl]pentanamide
Molecular weight	648.743
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.0
Synonyms	SCHEMBL14020512
Inchi Key	DYFZGWGXKHXHBT-YTTGMZPUSA-N
Inchi ID	InChI=1S/C36H37FN8O3/c37-26-12-14-27(15-13-26)43-18-20-44(21-19-43)35(47)25-11-16-31-30(23-25)42-34(45(31)32(33(38)46)10-5-17-41-36(39)40)24-6-4-9-29(22-24)48-28-7-2-1-3-8-28/h1-4,6-9,11-16,22-23,32H,5,10,17-21H2,(H2,38,46)(H4,39,40,41)/t32-/m0/s1
PubChem CID	59819634
ChEMBL	CHEMBL3717645
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<31622.8 nM	None	ChEMBL
Efficacy	25.0 %	None	ChEMBL

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