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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 5
Species	Mus musculus (Mouse)
Gene	Taar5
Synonym	mTaar5 PNR TAAR5 TaR-5 Trace amine receptor 5 Trimethylamine receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	337
Amino acid sequence	MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
UniProt	Q5QD14
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3784908
IUPHAR	170
DrugBank	N/A

Ligand

Name	CHEMBL1946780
Molecular formula	C28H32N2O2
IUPAC name	1-[(5,5-diphenyloxolan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Molecular weight	428.576
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.2
Synonyms	CHEMBL1962870 1-(5,5-Diphenyltetrahydrofuran-2-ylmethyl)-4-(2-methoxyphenyl)piperazine J3.595.106G BDBM50419718
Inchi Key	DKZVZJLNJPUMKG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H32N2O2/c1-31-27-15-9-8-14-26(27)30-20-18-29(19-21-30)22-25-16-17-28(32-25,23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15,25H,16-22H2,1H3
PubChem CID	56946573
ChEMBL	CHEMBL1962870
IUPHAR	N/A
BindingDB	50419718
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	4800.0 nM	MedChemComm, (2016) 7:2:353	ChEMBL

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