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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Mu-type opioid receptor
Species	Mus musculus (Mouse)
Gene	Oprm1
Synonym	opioid receptor, mu 1 opioid receptor OP3 Mu receptor MOR-1 MOPr MOP M-OR-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	398
Amino acid sequence	MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
UniProt	P42866
Protein Data Bank	4dkl, 5c1m, 6dde, 6ddf
GPCR-HGmod model	N/A
3D structure model	This structure is from PDB ID 4dkl.
BioLiP	BL0416752, BL0416751, BL0321492, BL0224753, BL0224754, BL0224755,BL0224756, BL0321491
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2858
IUPHAR	319
DrugBank	N/A

Ligand

Name	(2E,4E)-N-isobutyltetradeca-2,4-dienamide
Molecular formula	C18H33NO
IUPAC name	(2E,4E)-N-(2-methylpropyl)tetradeca-2,4-dienamide
Molecular weight	279.468
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	6.6
Synonyms	SCHEMBL15949868 2,4-Tetradecadienamide, N-isobutyl-, (E,E)- CHEMBL2442640 (2E,4E)-N-Isobutyl-2,4-tetradecadienamide N-Isobutyl-(2E,4E)-tetradeca-2,4-dienamide 2,4-Tetradecadienamide, N-(2-methylpropyl)-, (2E,4E)- AGJAUFUNZWHLKE-SQIWNDBBSA-N N-(2-Methylpropyl)-2,4-tetradecadienamide N-Isobutyl-(2E,4E)-tetradecadienamide 2,4-Tetradecadienamide, N-(2-methylpropyl)-, (E,E)- N-isobutyl-(2E,4E)-2,4-tetradecadienamide (E,E)-N-(2-Methylpropyl)-2,4-tetradecadienamide [ Show all ]
Inchi Key	AGJAUFUNZWHLKE-SQIWNDBBSA-N
Inchi ID	InChI=1S/C18H33NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-18(20)19-16-17(2)3/h12-15,17H,4-11,16H2,1-3H3,(H,19,20)/b13-12+,15-14+
PubChem CID	10731388
ChEMBL	CHEMBL2442640
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	51000.0 nM	PMID24095014	ChEMBL

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